Table 2.
Genotypic Distribution of TP53 (codon 72) and XPD (codon 751) in the Study Subject and Risk of Lung Cancer
Gene | Genotype | Control (n=200) n (%) |
Patient (n= 180) n (%) |
OR (95% CI) | P-value |
---|---|---|---|---|---|
TP53 | Arg/Arg | 74 (37.00) | 66 (36.67) | 1.0 (Ref.) | |
Arg/Pro | 116 (58.00) | 101 (56.11) | 0.976 (0.64-1.50) | 0.914 | |
Pro/ Pro | 10 (5.00) | 13 (7.22) | 1.458 (0.60-3.55) | 0.501 | |
XPD | Lys/Lys | 103 (51.50) | 80 (44.44) | 1.0 (Ref.) | |
Lys/Gln | 88 (44.00) | 75 (41.67) | 1.097 (0.72-1.68) | 0.745 | |
Gln/Gln | 9 (4.50) | 25 (13.89) | 3.576 (1.58-8.09) | 0.002* |
Odds ratios (OR) and 95% confidence interval (95%CI); *p<0.05 considered as level of significance.