Figure 2.

Representative Images of the Study's Histological in Experimental Groups (GII, GIII and GIV). A, Colonic mucosa stained with methylene blue, representing a topographic view of an ACF with seven AC. The AC presents an irregular luminal opening and a thicker epithelial lining compared to normal adjacent crypts (light microscopy - 4x objective). B/C: Colonic mucosa stained with H E representing a topographic view; B, hyperplastic crypts, with abundant glandular formations. The luminal opening of ACF was slightly elevated from the normal mucosa, presenting several elongated crypt layers; C, dysplastic AC (black arrow) presented cells with marked cytoplasmic basophilia; high nucleus-cytoplasm ratio and loss of cell polarity in several degrees, nuclear stratification; and reduction in mucin production