FIG 3.

FTY720 fails to alter Chlamydia induction of hydrosalpinx in upper genital tracts of C57BL/6J. (a and b) The same two groups of C57BL/6J mice (n = 15) as described in the Fig. 1 legend were sacrificed for observing genital pathology of the hydrosalpinx on day 56 after intravaginal infection. One gross image of the genital tract tissue is presented from each group, with vagina on the left and oviduct/ovary on the right. The hydrosalpinx is marked with a white arrow. The magnified oviduct/ovary images on the right are marked with the corresponding hydrosalpinx scores. (c) Hydrosalpinx severity scores are plotted. n = 15; data are from two independent experiments.