Table 1.
Characteristics | ΔPLT (×109/L) | P# value | P$ value | ||
---|---|---|---|---|---|
>-20, <20 | ≤ −20 | ≥20 | |||
N | 178 | 249 | 170 | ||
Age (yrs, median±SD) | 55.8 ± 11.3 | 51.8 ± 12.5 | 53.4 ± 12.2 | <0.001 | 0.042 |
Gender | 0.467 | 0.114 | |||
Male | 167 (93.8%) | 229 (92.0%) | 151 (88.8%) | ||
Female | 11 (6.2%) | 20 (8.0%) | 19 (11.2%) | ||
PS score | 0.666 | 0.72 | |||
0 | 148 (83.1%) | 203 (81.5%) | 139 (81.8%) | ||
1 | 30 (16.9%) | 46 (18.5%) | 31 (18.2%) | ||
Diameter of main tumour (cm) | 0.024 | 0.021 | |||
<5 | 108 (60.7%) | 123 (49.6%) | 82 (48.2%) | ||
≥5 | 70 (39.3%) | 125 (50.4%) | 88 (51.8%) | ||
AFP (ng/mL) | 0.03 | 0.285 | |||
<25 | 76 (44.4%) | 69 (33.5%) | 64 (38.8%) | ||
≥25 | 95 (55.6%) | 137 (66.5%) | 101 (61.2%) | ||
Hgb (g/L) | 0.91 | 0.107 | |||
<120 | 50 (28.1%) | 46 (27.5%) | 62 (36.5%) | ||
≥120 | 128 (71.9%) | 121 (72.5%) | 108 (63.5%) | ||
CRP (mg/L) | 0.035 | <0.001 | |||
<10 | 107 (66.0%) | 89 (54.6%) | 65 (44.5%) | ||
≥10 | 55 (34.0%) | 74 (45.4%) | 81 (55.5%) | ||
WBC (109/L) | 0.239 | 0.114 | |||
<11 | 166 (93.8%) | 150 (90.4%) | 150 (88.8%) | ||
≥11 | 11 (6.2%) | 16 (9.6%) | 19 (11.2%) | ||
No. of intrahepatic lesions | 0.404 | 0.224 | |||
0 | 55 (30.9%) | 62 (25.0%) | 41 (24.1%) | ||
≤3 | 46 (25.8%) | 69 (27.8%) | 40 (23.5%) | ||
>3 | 77 (43.3%) | 117 (47.2%) | 89 (52.4%) | ||
Location of lesions | 0.073 | 0.03 | |||
None | 55 (30.9%) | 62 (25.0%) | 41 (24.1%) | ||
Left/Right | 56 (31.5%) | 65 (26.2%) | 42 (24.7%) | ||
Both | 67 (37.6%) | 121 (48.8%) | 87 (51.2%) | ||
Child-Pugh class | <0.001 | 0.235 | |||
A | 87 (48.9.0%) | 5 (2.0%) | 10 (5.9%) | ||
B | 19 (10.7%) | 107 (43.0%) | 80 (47.1%) | ||
NA* | 72 (40.4%) | 137 (55.0%) | 80 (47.1%) |
Notes: ΔPLT=the change value of platelet count after TACE. Differences are compared using the chi-square test for categorical measures and Kruskal–Wallis Test for continuous measures. Numbers that do not add up to 597 are attributable to missing data. #ΔPLT≤-20 vs ΔPLT within±20. $ΔPLT≥20 vs ΔPLT within±20. *Include 3 patients with class Child-Pugh C.