Table 2.
Univariate Analysis for Risk Factors of OS After TACE Treatment
| ΔPLT≥20 (×109/L) | ΔPLT≤-20 (×109/L) | |||
|---|---|---|---|---|
| Statistics | HR (95% CI) | Statistics | HR (95% CI) | |
| Gender | ||||
| Male | 318 (91.38%) | 1 | 396 (92.74%) | 1 |
| Female | 30 (8.62%) | 1.35 (0.83, 2.20) | 31 (7.26%) | 1.17 (0.72, 1.89) |
| Age (yrs) | ||||
| <55 | 148 (42.53%) | 1 | 201 (47.07%) | 1 |
| ≥55 | 200 (57.47%) | 0.98 (0.74, 1.30) | 226 (52.93%) | 0.88 (0.69, 1.14) |
| PS score | ||||
| 0 | 287 (82.47%) | 1 | 351 (82.20%) | 1 |
| 1 | 61 (17.53%) | 3.17 (2.24, 4.48) | 76 (17.80%) | 2.16 (1.58, 2.96) |
| Diameter of main tumour (cm) | ||||
| <5 | 190 (54.60%) | 1 | 231 (54.10%) | 1 |
| ≥5 | 158 (45.40%) | 2.76 (2.08, 3.68) | 196 (45.90%) | 2.87 (2.22, 3.71) |
| AFP (ng/mL) | ||||
| <25 | 140 (40.23%) | 1 | 145 (33.96%) | 1 |
| ≥25 | 196 (56.32%) | 2.58 (1.90, 3.50) | 232 (54.33%) | 2.29 (1.72, 3.06) |
| NA | 12 (3.45%) | 1.65 (0.71, 3.81) | 50 (11.71%) | 1.20 (0.76, 1.88) |
| Hgb (g/L) | ||||
| <120 | 112 (32.18%) | 1 | 96 (27.83%) | 1 |
| ≥120 | 236 (67.82%) | 0.65 (0.48, 0.86) | 249 (72.17%) | 0.79 (0.58, 1.08) |
| CRP (mg/L) | ||||
| <10 | 172 (49.43%) | 1 | 196 (45.90%) | 1 |
| ≥10 | 136 (39.08%) | 1.97 (1.46, 2.65) | 129 (30.21%) | 1.77 (1.32, 2.35) |
| NA | 40 (11.49%) | 1.34 (0.84, 2.12) | 102 (23.89%) | 1.21 (0.87, 1.67) |
| WBC (109/L) | ||||
| <11 | 316 (91.33%) | 1 | 316 (92.13%) | 1 |
| ≥11 | 30 (8.67%) | 1.64 (1.03, 2.60) | 27 (7.87%) | 1.18 (0.72, 1.94) |
| No. of intrahepatic lesions | ||||
| 0 | 96 (27.59%) | 1 | 117 (27.40%) | 1 |
| ≤3 | 86 (24.71%) | 2.02 (1.33, 3.05) | 115 (26.93%) | 1.58 (1.09, 2.28) |
| >3 | 166 (47.70%) | 3.06 (2.11, 4.44) | 195 (45.67%) | 3.02 (2.18, 4.18) |
| Location of Lesions | ||||
| None | 96 (27.59%) | 1 | 117 (27.40%) | 1 |
| Left/Right | 98 (28.16%) | 2.01 (1.34, 3.02) | 121 (28.34%) | 1.54 (1.06, 2.23) |
| Both | 154 (44.25%) | 3.17 (2.18, 4.62) | 188 (44.26%) | 3.07 (2.21, 4.25) |
| Child-Pugh class | ||||
| A | 164 (47.13%) | 1 | 174 (40.75%) | 1 |
| B | 32 (9.20%) | 1.50 (0.92, 2.44) | 45 (10.54%) | 1.58 (1.06, 2.35) |
| NA | 152 (43.68%) | 0.99 (0.74, 1.33) | 208 (48.71%) | 0.92 (0.70, 1.21) |
Note: Numbers that do not add up to 348 (ΔPLT ≥20 vs ΔPLT±20) or 427 (ΔPLT≤-20 vs ΔPLT±20) are attributable to missing data.