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. 2020 Oct 6;10:557157. doi: 10.3389/fonc.2020.557157

FIGURE 1.

FIGURE 1

The different IFI44 expression in multiple cancers. (A) The different IFI44 expression in TCGA Pan-cancer samples including tumor and normal tissues analyzed by TIMER database. (B) The overexpression of IFI44 in head and neck squamous cell carcinoma (HNSC) tumor section was confirmed in three GEO datasets (GSE107591, 45 normal vs. 167 cancer, P < 0.0001; GSE30784, 23 normal vs. 24 cancer, P = 0.0076; GSE138206, 12 normal vs. 6 cancer, P = 0.0023). (C) Human papillomavirus (HPV)-positive oral cavity carcinoma (OCC) expressed higher IFI44 than normal samples (GSE112026, 25 normal vs. 47 cancer, P < 0.0001). (D) IFI44 was highly expressed in HNSC relapsed samples than non-relapsed patients (non-relapsed, n = 351; relapsed, n = 133, P = 0.0315). (E) Expression of IFI44 proteins in different tumor tissues and paired normal tissues in HNSC by immunohistochemistry assay. (P-value significant codes: *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).