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. 2020 Oct 6;11:575577. doi: 10.3389/fimmu.2020.575577

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Copyright © 2020 Chernomordik, Cercek, Lio, Mihailovic, Yano, Herscovici, Zhao, Zhou, Chyu, Shah and Dimayuga.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune checkpoint PDCD1 mRNA expression and correlation in T Effector response to LL-37 and cat-hCAP-18. Programmed cell death protein 1 (PDCD1) mRNA expression in peripheral blood mononuclear cells stimulated with the human antimicrobial peptide LL-37 (A) or the cathelin domain of the proprotein hCAP-18, cat-hCAP-18 (B). Control N = 6; Stable = 5; ACS = 5. *P < 0.05 (ACS vs Control; Kruskal-Wallis and Dunn’s multiple comparisons test). Correlation plot between CD8+ T Effector response to LL-37 and cat-hCAP-18 (C). Correlation plot between CD4+ T Effector response to LL-37 and cat-hCAP-18 (D).