Table 1. Baseline Characteristics of Older Adults With Sarcopenia.
Characteristic | Mean (SD) | |
---|---|---|
Bimagrumab (nā=ā113) | Placebo (nā=ā67) | |
Age, y | 79.5 (5.46) | 78.3 (5.03) |
Median (range) | 79 (70-95) | 78 (70-88) |
Sex, No. (%) | ||
Men | 47 (41.6) | 24 (35.8) |
Women | 66 (58.4) | 43 (64.2) |
Race, No. (%) | ||
White | 93 (82.3) | 54 (80.6) |
Asian | 17 (15.0) | 11 (16.4) |
Other | 0 | 1 (1.0) |
Ethnicity, No. (%) | ||
Other | 56 (49.6) | 31 (46.3) |
Not Hispanic/Latino | 30 (26.5) | 16 (23.9) |
Hispanic/Latino | 19 (16.8) | 19 (28.4) |
Height, cm | 163.6 (12.50) | 161.9 (9.55) |
Median (range) | 162 (138-200) | 160 (145-184) |
Weight, kg | 65.6 (16.61) | 62.3 (11.17) |
Median (range) | 63.4 (36-111) | 62.8 (42-94) |
BMI | 24 (3.55) | 23.6 (2.84) |
Median (range) | 24 (15-32) | 23.6 (17-31) |
Total SPPB score | 7.1 (1.73) | 7.3 (1.68) |
6MWD, m | 294.3 (83.60) | 312.4 (93.92) |
Gait speed, m/s | 0.642 (0.1079) | 0.656 (0.0836) |
Grip strength, kg | ||
Right hand | 20.4 (7.79) | 19.5 (7.36) |
Left hand | 19.4 (7.63) | 18.1 (7.09) |
LBM, kg | 35.4 (8.89) | 33.6 (6.89) |
FBM, kg | 22.7 (8.74) | 21.2 (7.5) |
ASMI, kg/m2 | 5.7 (0.82) | 5.5 (0.75) |
Non-Asia | ||
Men | 6.64 (0.421) | 6.38 (0.586) |
Women | 5.13 (0.351) | 5.07 (0.373) |
Asia | ||
Men | 6.12 (0.628) | 6.29 (0.527) |
Women | 4.92 (0.213) | 5.33 (0.265) |
Abbreviations: 6MWD, 6-minute walk distance; ASMI, appendicular skeletal muscle index (calculated as lean mass of upper and lower extremities in kilograms divided by height in meters squared); BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); FBM, fat body mass; LBM, lean body mass; SPPB, Short Physical Performance Battery.