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. 2020 Oct 19;78(2):1–12. doi: 10.1001/jamaneurol.2020.3921

Table 2. Comparison of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and Mayo Clinic Study of Aging (MCSA) Baseline and Annual Change Values in Entorhinal Cortex (ERC) and Inferior Temporal (IT) Regions of Interest.

Outcome Mean (SD)
<8 CL 9-21 CL 22-67 CL >68 CL
Participants, No. (%)
ADNI 32 (28) 18 (16) 36(32) 28 (25)
MCSA 24 (14) 70 (42) 42 (25) 31 (19)
Baseline flortaucipir SUVR
ERC
ADNI 1.101 (0.088) 1.167 (0.108) 1.167 (0.112) 1.261 (0.180)
MCSA 1.068 (0.115) 1.088 (0.096) 1.112 (0.092) 1.346 (0.263)
IT
ADNI 1.184 (0.078) 1.222 (0.096) 1.251 (0.155) 1.323 (0.181)
MCSA 1.193 (0.094) 1.228 (0.078) 1.246 (0.078) 1.335 (0.172)
Annual change in flortaucipir SUVR
ERC
ADNI 0.015 (0.057) –0.011 (0.076) 0.008 (0.037) 0.014 (0.045)
MCSA –0.001 (0.029) 0.007 (0.019) 0.007 (0.021) 0.032 (0.039)
IT
ADNI 0.019 (0.057) –0.021 (0.069) 0.013 (0.029) 0.030 (0.051)
MCSA –0.004 (0.022) 0.004 (0.016) 0.005 (0.022) 0.030 (0.033)

Abbreviation: CL, centiloid; SUVR, standardized uptake value ratio.