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Learning impairment in aging mice induced by sleep deprivation was prevented with SS31. Mice were given four trials to escape the box maze for a maximum of 2 min each, and their escape times were recorded. The data represent the mean ± SEM (n = 10 per group). *** p < 0.001, statistically significant difference between SD group/SD + Saline group and Non-SD group. ### p < 0.001, statistically significant difference between SD + SS31 group and SD group/SD + Saline group.
