. Author manuscript; available in PMC: 2020 Oct 20.

Published in final edited form as: J Mech Behav Biomed Mater. 2018 Oct 11;90:125–132. doi: 10.1016/j.jmbbm.2018.10.010

Table 1.

Elemental composition obtained by Quantitative Energy Dispersive X-ray Spectrometry.

Ratios	Wild-type (mean ± SD)		Δ (%)	Brtl/+ (mean ± SD)
Ratios	ER	PR	Δ (%)	ER	PR	Δ (%)
Ca/P	1.527 ± 0.0097	1.512 ± 0.0065	− 0.96 ^*	1.529 ± 0.0114	1.512 ± 0.0095	− 1.07^*
Na/Ca	0.041 ± 0.0027	0.05 ± 0.0017	21.68^{* *}	0.042 ± 0.0023	0.049 ± 0.004	16.2^*
Mg/Ca	0.027 ± 0.0004	0.03 ± 0.0014	10.64^{* *}	0.027 ± 0.001	0.029 ± 0.0008	9.17 ^{* *}
K/Ca	0.006 ± 0.0017	0.008 ± 0.0012	33.2^{* *}	0.006 ± 0.0012	0.008 ± 0.0016	24.73 ^*

Significant elemental ratio differences were found between endocortical (ER) and periosteal (PR) region in both wild-type and Brtl/+ mice but not between these both groups.

p < 0.05 vs ER

^{* *}

p < 0.01 vs ER

^{* *}

p < 0.001.