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. 2020 Oct 20;20:782. doi: 10.1186/s12879-020-05509-2

Table 3.

Laboratory findings of 185 inpatients with culture confirmed herpetic gingivostomatitis

Laboratory data Total Late Diagnosis Early Diagnosis Other Diagnosis P-value
Case Number 185 74 65 46
Hemogram
 WBC count (1000/μL)a 12.44 ± 4.95 13.05 ± 5.35 12.43 ± 4.77 11.46 ± 4.44 0.229
 WBC count-peakb 12.47 ± 4.89 13.12 ± 5.31 12.41 ± 4.65 11.49 ± 4.4 0.209
 WBC count-nadir 10.64 ± 4.01 10.96 ± 3.70 10.98 ± 4.05 9.62 ± 4.34 0.147
  < 5000/μL (No. (%)) 6 (3.2) 1 (1.4) 2 (3.1) 3 (6.5) 0.315
  > 15,000/μL (No. (%)) 52 (28.1) 23 (31.1) 19 (29.2) 10 (21.7) 0.525
 Platelet (1000/μL) 251.72 ± 73.0 260.57 ± 66.42 253.25 ± 64.26 235.37 ± 91.25 0.181
  < 150,000/μL (No. (%)) 10 (5.4) 3 (4.1) 2 (3.1) 5 (10.9) 0.167
  > 450,000/μL (No. (%)) 4 (2.2) 1 (1.4) 0 3 (6.5) 0.057
Biochemistry
 CRP (mg/L)a 40.31 ± 37.47 40.00 ± 40.24 35.52 ± 34.68 47.48 ± 36.31 0.256
 CRP-peak (mg/L)b [Range] 41.86 ± 38.15 [1.3–193.09] 40.51 ± 40.01 [2.1–193.09] 37.78 ± 36.73 [1.3–165.97] 49.7 ± 36.7 [1.4–132.7] 0.252
  < 40 mg/L (No. (%)) 130 (71.0) 51 (69.9) 48 (75) 31 (67.4) 0.659
  > 100 mg/L (No. (%)) 17 (9.3) 8 (11.0) 4 (6.2) 5 (10.9) 0.564
 BUN (mg/dL) 8.8 ± 2.83 9.05 ± 3.09 8.67 ± 2.26 8.61 ± 3.07 0.876
 Cr (mg/dL) 0.14 ± 0.35 0.07 ± 0.25 0.08 ± 0.28 0.31 ± 0.47 0.006
  > 1.0 mg/dL (No. (%)) 0 0 0 0 NA
 AST (U/L) [Range] 38.39 ± 42.1 [15–434] 44.18 ± 56.49 [16–434] 32.4 ± 8.72 [17–58] 41.00 ± 40.62 [15–246] 0.369
  > 3-folds normal value (No. (%)) 3 (2.6) 2 (3.6) 0 1 (6.2) 0.32
 Sugar (mg/dL) 94.61 ± 33.46 90.07 ± 15.31 89.36 ± 16.84 108.5 ± 58.88 0.06
  Hypoglycemia (< 60) (No. (%)) 1 (1.2) 1 (2.5) 0 0 0.603

aFirst laboratory exam on admission

bThe highest or lowest laboratory value during hospitalization

Abbreviations: WBC White blood cell, Hb Hemoglobin, CRP C-reactive protein, BUN Blood urea nitrogen, Cr Creatinine, AST Aspartate aminotransferase