Table 3.
Laboratory data | Total | Late Diagnosis | Early Diagnosis | Other Diagnosis | P-value |
---|---|---|---|---|---|
Case Number | 185 | 74 | 65 | 46 | |
Hemogram | |||||
WBC count (1000/μL)a | 12.44 ± 4.95 | 13.05 ± 5.35 | 12.43 ± 4.77 | 11.46 ± 4.44 | 0.229 |
WBC count-peakb | 12.47 ± 4.89 | 13.12 ± 5.31 | 12.41 ± 4.65 | 11.49 ± 4.4 | 0.209 |
WBC count-nadir | 10.64 ± 4.01 | 10.96 ± 3.70 | 10.98 ± 4.05 | 9.62 ± 4.34 | 0.147 |
< 5000/μL (No. (%)) | 6 (3.2) | 1 (1.4) | 2 (3.1) | 3 (6.5) | 0.315 |
> 15,000/μL (No. (%)) | 52 (28.1) | 23 (31.1) | 19 (29.2) | 10 (21.7) | 0.525 |
Platelet (1000/μL) | 251.72 ± 73.0 | 260.57 ± 66.42 | 253.25 ± 64.26 | 235.37 ± 91.25 | 0.181 |
< 150,000/μL (No. (%)) | 10 (5.4) | 3 (4.1) | 2 (3.1) | 5 (10.9) | 0.167 |
> 450,000/μL (No. (%)) | 4 (2.2) | 1 (1.4) | 0 | 3 (6.5) | 0.057 |
Biochemistry | |||||
CRP (mg/L)a | 40.31 ± 37.47 | 40.00 ± 40.24 | 35.52 ± 34.68 | 47.48 ± 36.31 | 0.256 |
CRP-peak (mg/L)b [Range] | 41.86 ± 38.15 [1.3–193.09] | 40.51 ± 40.01 [2.1–193.09] | 37.78 ± 36.73 [1.3–165.97] | 49.7 ± 36.7 [1.4–132.7] | 0.252 |
< 40 mg/L (No. (%)) | 130 (71.0) | 51 (69.9) | 48 (75) | 31 (67.4) | 0.659 |
> 100 mg/L (No. (%)) | 17 (9.3) | 8 (11.0) | 4 (6.2) | 5 (10.9) | 0.564 |
BUN (mg/dL) | 8.8 ± 2.83 | 9.05 ± 3.09 | 8.67 ± 2.26 | 8.61 ± 3.07 | 0.876 |
Cr (mg/dL) | 0.14 ± 0.35 | 0.07 ± 0.25 | 0.08 ± 0.28 | 0.31 ± 0.47 | 0.006 |
> 1.0 mg/dL (No. (%)) | 0 | 0 | 0 | 0 | NA |
AST (U/L) [Range] | 38.39 ± 42.1 [15–434] | 44.18 ± 56.49 [16–434] | 32.4 ± 8.72 [17–58] | 41.00 ± 40.62 [15–246] | 0.369 |
> 3-folds normal value (No. (%)) | 3 (2.6) | 2 (3.6) | 0 | 1 (6.2) | 0.32 |
Sugar (mg/dL) | 94.61 ± 33.46 | 90.07 ± 15.31 | 89.36 ± 16.84 | 108.5 ± 58.88 | 0.06 |
Hypoglycemia (< 60) (No. (%)) | 1 (1.2) | 1 (2.5) | 0 | 0 | 0.603 |
aFirst laboratory exam on admission
bThe highest or lowest laboratory value during hospitalization
Abbreviations: WBC White blood cell, Hb Hemoglobin, CRP C-reactive protein, BUN Blood urea nitrogen, Cr Creatinine, AST Aspartate aminotransferase