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. 2020 Sep 18:1–9. doi: 10.1159/000511324

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Copyright © 2020 by S. Karger AG, Basel

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Fig. 1 — Findings of the placenta with manifest COVID-19. a Macroscopic image showing inhomogeneous and unusually condensed placental parenchyma and an area of infarction (arrow). b Chronic villitis and intervillositis (haematoxylin and eosin [H&E], 40×). c, d Characterisation of the inflammatory infiltrate consisting primarily of cytotoxic T-cells expressing CD8 (c) and fewer macrophages expressing CD68 (d) (immunohistochemistry, 200×). e, f Lymphohistiocytic villitis resulting in chorionic vasculitis and subsequent fresh (e) and already organizing thrombosis (f) (H&E, 100×). g Intervillous increase of fibrin as result of maternal malperfusion (H&E, 100×). h Presence of SARS-CoV-2 in decidual cells (red) (in situ hybridization for SARS-CoV-2, 200×).