Fig. 2.

Findings of placentas with no presence of SARS-CoV-2 at the time of delivery and expression of ACE2. a Features of subtle chronic villitis in patient 5 showing acute chorioamnionitis as major finding. The lymphohistiocytic infiltrate was sparse in contrast to patient 2 (H&E, 100×). b Decidual arteriopathy in patient 1: decidual artery showing complete necrosis of the arterial wall and intraluminal fibrosis. The patient did not show evidence of preeclampsia or gestation-related hypertension. c Foetal vessel in patient 1 showing a small thrombus. In contrast to patient 2, the thrombus was not wall-adherent and there were no signs of vasculitis (H&E, 200×). c, d Immunohistochemistry for ACE2 showing weak expression in the extravillous invasive trophoblast (immunohistochemistry, 40×).