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Glomerulosclerosis in DN (A) and FSGS (B). Light microscopy photomicrographs of a glomerulus showing DN with characteristic nodular mesangial expansion (Kimmelstiel-Wilson lesions) (Periodic acid–Schiff staining) (A), and of a glomerulus with mild FSGS (methenamine-silver staining) (B). Nuclei are stained in blue. Both glomeruli presenting glomerulosclerosis with increased glomerular extracellular matrix deposition and obliteration of capillaries. Scale bars represent 50 µm.
