Table 1.
Univariate logistic regression analysis of patients with or without stroke recurrence at 1 year after MIS
| Variables | Overall N = 1121 |
Recurrence N = 38 (3.4%) | No recurrence N = 1083 (96.6%) |
OR (95% CI) | P value |
|---|---|---|---|---|---|
| Demographic information | |||||
| Age, median (IQR), year | 64.0 (56.0–74.0) | 70.0 (61.2–76.8) | 64.0 (55.0–73.0) | 1.05 (1.02–1.08) | 0.001 |
| Male, n(%) | 697 (62.2) | 29 (76.3) | 668 (61.7) | 1.97 (0.93–4.17) | 0.075 |
| BMI on admission,kg/m2 | 23.9 (22.2–25.6) | 24.1 (22.6–26.1) | 23.9 (22.1–25.6) | 1.00 (0.90–1.10) | 0.935 |
| Education level, n(%) | 0.068 | ||||
| elementary or below | 446 (39.8) | 18 (47.4) | 428 (39.5) | Ref. | – |
| middle school | 234 (20.9) | 6 (15.8) | 228 (21.1) | 0.62 (0.25–1.57) | 0.319 |
| high school or above | 441 (39.3) | 14 (36.8) | 427 (39.4) | 0.78 (0.39–1.57) | 0.485 |
| Medical insurance type, n(%) | 0.636 | ||||
| Urban employees’ medical insurance | 591 (52.7) | 19 (50.0) | 572 (52.8) | Ref. | – |
| New type rural cooperative medical system | 414 (36.9) | 17 (44.7) | 397 (36.7) | 1.29 (0.67–2.48) | 0.443 |
| Commercial insurance | 2 (0.2) | 0 (0.0) | 2 (0.2) | 0.00 (0.00-∞) | 0.996 |
| Out-of-pocket medical | 114 (10.2) | 2 (5.3) | 112 (10.3) | 0.55 (0.13–2.35) | 0.418 |
| Vascular risk factors | – | ||||
| Hypertension, n(%) | 768 (68.5) | 26 (68.4) | 742 (68.5) | 0.99 (0.50–1.96) | 0.974 |
| DM, n(%) | 242 (21.6) | 12 (31.6) | 230 (21.2) | 1.68 (0.85–3.32) | 0.139 |
| Dyslipidemia, n(%) | 77 (6.9) | 1 (2.6) | 76 (7.0) | 0.36 (0.05–2.65) | 0.318 |
| AF, n(%) | 54 (4.8) | 3 (7.9) | 51 (4.7) | 1.69 (0.52–5.48) | 0.386 |
| Smoking, n(%) | 0.017 | ||||
| Never smoking | 665 (59.3) | 12 (31.6) | 653 (60.3) | Ref. | – |
| smoking cessation | 169 (15.1) | 9 (23.7) | 160 (14.8) | 1.85 (0.89–4.38) | 0.068 |
| Current smoking | 287 (25.6) | 17 (44.7) | 270 (24.9) | 1.24 (1.11–2.96) | 0.034 |
| Moderate or heavy alcohol use, n(%) | 271 (24.2) | 7 (18.4) | 264 (24.4) | 0.70 (0.31–1.59) | 0.391 |
| Previous stroke, n(%) | 297 (26.5) | 18 (47.4) | 279 (25.8) | 2.54 (1.34–4.80) | 0.004 |
| PVD, n(%) | 29 (2.6) | 3 (7.9) | 26 (2.4) | 3.35 (1.03–10.91) | 0.044 |
| Pneumonia, n(%) | 25 (2.2) | 6 (15.8) | 19 (1.8) | 9.89 (4.13–23.68) | 0.001 |
| NIHSS score on admission | 1.0 (0.0–2.0) | 1.5 (0.0–3.0) | 1.0 (0.0–2.0) | 1.04 (0.80–1.37) | 0.755 |
| SBP on admission, mmHg | 144.8 ± 20.7 | 145.6 ± 24.2 | 144.8 ± 20.6 | 1.00 (0.99–1.02) | 0.788 |
| DBP on admission, mmHg | 85.7 ± 12.2 | 86.6 ± 14.6 | 85.7 ± 12.1 | 1.01 (0.98–1.03) | 0.661 |
| Heart rate, bmp | 74.3 ± 9.4 | 76.8 ± 10.0 | 74.2 ± 9.3 | 1.03 (1.00–1.06) | 0.086 |
| Laboratory findings | |||||
| Total cholesterol, mmol/L | 4.4 ± 1.0 | 4.5 ± 0.9 | 4.4 ± 1.0 | 1.04 (0.76–1.41) | 0.821 |
| Triglyceride, mmol/L | 1.7 ± 1.2 | 1.6 ± 0.9 | 1.7 ± 1.2 | 0.91 (0.65–1.26) | 0.560 |
| HDL-C, mmol/L | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 | 0.57 (0.18–1.79) | 0.337 |
| LDL-C, mmol/L | 2.6 ± 0.8 | 2.8 ± 0.7 | 2.6 ± 0.9 | 1.19 (0.84–1.68) | 0.332 |
| FBG, mmol/L | 5.8 ± 2.1 | 6.2 ± 3.0 | 5.7 ± 2.1 | 1.09 (0.97–1.22) | 0.169 |
| BUN, mmol/L | 5.0 ± 1.8 | 5.3 ± 1.7 | 5.0 ± 1.8 | 1.08 (0.93–1.26) | 0.321 |
| UA, 10 μmol/L | 291.3 ± 96.0 | 277.9 ± 95.8 | 291.8 ± 96.1 | 0.98 (0.95–1.02) | 0.387 |
| ALP, U/L | 77.6 ± 25.6 | 83.8 ± 21.5 | 77.3 ± 25.7 | 1.01 (1.00–1.02) | 0.104 |
| BPC, × 1011/L | 194.4 ± 58.3 | 193.4 ± 48.0 | 194.4 ± 58.6 | 0.97 (0.55–1.71) | 0.906 |
| Leukocyte count, ×109/L | 6.7 ± 2.2 | 7.1 ± 2.5 | 6.6 ± 2.2 | 1.08 (0.95–1.21) | 0.234 |
Abbreviations: BMI Body Mass Index, DM Diabetes Mellitus, AF Atrial Fibrillation, PVD Peripheral Vascular Disease, NIHSS National Institutes of Health Stroke Scale, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, HLD-C High-Density Lipoprotein Cholesterol, LDL-C low-density lipoprotein cholesterol, FBG Fasting Blood Glucose, BUN Blood Urea Nitrogen, UA Uric Acid, ALP Alkaline Phosphatase, BPC Blood Platelet Count, CI confidence internals, OR odds ratios, IQR interquartile range