Table 2.

Median and interquartile ranges or mean ± SD of various echocardiographic parameters in rhesus macaques in the control, HCM, and OCD groups.

	Overall	Control	HCM	OCD	P value (overall)	Control compared with HCM	Control compared with OCD	HCM compared with OCD
LA/Ao (sax)	1.5 ± 0.21	1.4 ± 0.19	1.4 ± 0.22	1.64 (1.53–1.83)	0.024a	>0.99	0.02a	0.052
LA/Ao (lax)	2.1 ± 0.28	2.1 ± 0.25	2.07 ± 0.29	2.36 (2.33–2.72)	<0.0001a	>0.99	<0.0001a	0.0006a
IVSd (cm)	0.51 (0.43–0.59)	0.48 ± 0.097	0.68 ± 0.13	0.58 (0.53–0.64)	<0.0001a	<0.0001a	0.056	0.79
LVPWd (cm)	0.58 (0.49–0.67)	0.56 ± 0.1	0.79 ± 0.14	0.72 (0.58–0.77)	<0.0001a	<0.0001a	0.014a	>0.99
FS (%)	38 ± 9.0	37.9 ± 8.3	44.4 (35.9–47.9)	34.4 (22.3–36.5)	0.025a	0.03a	0.13	0.0037a
EF (%)	70.5 (63.3–78.0)	70.2 (62.0–76.8)	78.8 (68.1–81.9)	65.2 (45.5–68.3)	0.0043a	0.046*	0.18	0.004*
E’/A’ (medial)	1.3 ± 0.43	0.94 ± 0.02	0.92 ± 0.24	0.98 (0.68–1.72)	0.0019a	0.0016a	0.81	0.84
E’/A’ (lateral)	1.5 (1.0–1.8)	0.65 ± 0.021	8.37 (7.6–12.3)	1.23 (0.59–1.52)	0.0018a	0.0044a	0.17	>0.99
VAo (m/s)	1.2 (1.1–1.4)	1.23 ± 0.17	1.36 (1.21–1.69)	1.1 (1.01–1.47)	0.0061a	0.0058a	>0.99	0.11
E/A	1.3 (0.9–1.5)	1.84 (1.44-2.1)	0.86 (0.76–0.99)	1.09 (0.86–1.56)	<0.0001a	<0.0001a	>0.99	0.23

^a significant difference (P < 0.05). E/A = ratio of the peak early to late transmitral flow velocity, E’/A’(lateral) = ratio of the peak early to late lateral mitral annular filling velocity, E’/A’(medial) = ratio of the peak early to late medial mitral annular filling velocity, HCM = hypertrophic cardiomyopathy; IVSd = interventricular septal wall thickness during diastole; LA/Ao (lax) = left atrial diameter to left aortic root diameter ratio from right parasternal long-axis view, LA/Ao (sax) = left atrial diameter to left aortic root diameter ratio from right parasternal short-axis view; LVPWd = thickness of left ventricular posterior wall during diastole, OCD = other cardiac disease, V_Ao = peak velocity for aortic flow