Table 4.

cTnI cut-off values with the sensitivity, specificity, and likelihood ratio to differentiate rhesus macaques with and without any cardiac diseases.

cTnI (ng/mL)	Sensitivity	95% CI	Specificity	95% CI	Likelihood ratio
> 0.0065	0.68	0.49–0.82	0.87	0.79–0.92	5.3
> 0.0075	0.68	0.49–0.82	0.91	0.84–0.95	7.6
> 0.0085	0.68	0.49–0.82	0.94	0.88–0.97	11
> 0.0095	0.64	0.46–0.79	0.95	0.89–0.98	13
> 0.011	0.61	0.42–0.76	0.95	0.89–0.98	12
> 0.012	0.54	0.36–0.70	0.95	0.89–0.98	11
> 0.013	0.54	0.36–0.70	0.97	0.92–0.99	18
> 0.014	0.46	0.30–0.64	0.97	0.92–0.99	16
> 0.017	0.43	0.27–0.61	0.97	0.92–0.99	14
> 0.021	0.39	0.24–0.58	0.98	0.93–1.0	20
> 0.025	0.36	0.21–0.54	0.98	0.93–1.0	18
> 0.031	0.36	0.21–0.54	0.99	0.93–1.0	36
> 0.034	0.32	0.18–0.51	0.99	0.93–1.0	32
> 0.044	0.29	0.15–0.47	0.99	0.93–1.0	29
> 0.055	0.29	0.15–0.47	1	0.93–1.0
> 0.057	0.25	0.13–0.43	1	0.93–1.0
> 0.060	0.21	0.10–0.40	1	0.93–1.0
> 0.062	0.18	0.079–0.36	1	0.93–1.0
> 0.076	0.14	0.057–0.31	1	0.93–1.0
> 0.093	0.11	0.037–0.27	1	0.93–1.0
> 0.14	0.071	0.013–0.23	1	0.93–1.0
> 0.29	0.036	0.0018–0.18	1	0.93–1.0

The optimal cut-off value of cTnI was determined to be 0.0085 with the sensitivity of 68% and the specificity of 94% based on the Youden Index J. cTnI = cardiac troponin I