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. 2020 Oct 6;7:528. doi: 10.3389/fmed.2020.00528

Table 4.

Risk factors for severe sleep disturbance among patients who received dexmedetomidine therapy under general anesthesia and non-general anesthesia in a stepwise logistic regression analysis model.

Population Factors with statistical significance P-value OR 95% CI Model P-value
General anesthesia (n = 2,050) <0.001
Intraoperative dexmedetomidine dose (Ref. High-DEX) <0.001 0.39 0.27–0.57
Surgery type (Ref. other type surgery)
Abdominal surgery 0.369 0.38 0.56–1.24
Orthopedic surgery <0.001 1.93 1.37–2.72
Urological surgery 0.527 0.85 0.52–1.40
Non-general anesthesia (n = 925) 0.022
Intraoperative dexmedetomidine dose (Ref. High-DEX) 0.026 0.59 0.37–0.94
Receiving PCIA (Ref. yes) 0.002 2.22 1.34–3.69

OR, odds rate; CI, confidence interval; PCIA, patient-controlled intravenous analgesia; Ref., reference.