Table 2: Summary of proteins associated with at least one approved drug and identified by SDREM from both time-series bulk and single-cell SARS-CoV-2.

For each human protein, we show SDREM-based minimum rank between the bulk and single-cell lists, whether or not it is a known SARS-CoV-2 and a pair of associated approved drug names derived from ChEMBL25, IUPHAR/BPS Guide to Pharmacology, Pharos, or ZINC.

Gene name	SDREM minRank	SARS-CoV-2 interactor?	Approved drug names
RELA	11	N	bortezomib
NFKB2	26	N	bortezomib
DNMT1	31	Y	azacitidine; decitabine
BRD4	32	Y	alprazolam ; fedratinib
ERBB2	45	Y	afatinib; neratinib