Skip to main content
. Author manuscript; available in PMC: 2020 Oct 20.
Published in final edited form as: Chem Res Toxicol. 2020 Sep 9;33(9):2475–2486. doi: 10.1021/acs.chemrestox.0c00265

Figure 1.

Figure 1.

AP sites, N7POBG and O2POBdT in lung and liver of control rats and rats treated with 5.2 mg/kg or 20.7 mg/kg NNK for 4 days by subcutaneous injection (total doses 20.8 and 82.8 mg/kg). Rats were sacrificed four h after the final dose. Increases in AP sites were observed in both exposure groups in liver and lung (*indicates exposure is significantly higher than control at 95% confidence interval). N7POBG and O2POBdT were not detected in the control tissues.