Table 4.
Testing results, comparing RT-LAMP method on deep nasal swabs to Multiplex tandem RT-PCR performed on both pharyngeal and deep nasal swabs
| PCR (repeat) | |||
|---|---|---|---|
| Positive | Negative | Total | |
| LAMP | |||
| Positive | 8 | 0 | 8 |
| Negative | 2 | 11 | 13 |
| Total | 10 | 11 | 21 |
| LAMP single test including low positives | |||
| Positive | 8 | 3 | 11 |
| Negative | 2 | 8 | 10 |
| 10 | 11 | 21 | |
| (95% CI) | |||
| Sensitivity single test | 80% | (44–98%) | |
| Specificity single test | 73% | (39–94%) | |
| Positive Predictive Value | 73% | (39–94%) | |
| Negative Predictive Value | 80% | (44–98%) | |
| Sensitivity – 2 LAMP tests | 80% | (44 to 97%) | |
| Specificity – 2 LAMP tests | 100% | (72 to 100%) | |
| PPV – 2 LAMP tests | 100% | (n/a) | |
| NPV – 2 LAMP tests | 85% | (61 to 95%) | |
Positive PCR cases are defined as at least one positive test over 2 days.