TABLE 2.
Gastrointestinal symptoms and comorbidities reported by eosinophilic gastrointestinal disease type
| EGID type |
|||
|---|---|---|---|
| Symptom/comorbidity | EoE only, n (%) | EG, EGE, or EC,* n (%) | P |
| Nausea | |||
| Never | 115 (22.8) | 16 (9.3) | <0.0001 |
| Infrequently/quarterly | 104 (20.6) | 29 (16.8) | |
| Monthly | 93 (18.5) | 20 (11.6) | |
| Weekly | 111 (22.0) | 44 (25.4) | |
| Daily | 81 (16.1) | 64 (37.0) | |
| Vomiting or regurgitation | |||
| Never | 102 (19.9) | 25 (14.5) | 0.18 |
| Infrequently/quarterly | 140 (27.3) | 51 (29.7) | |
| Monthly | 109 (21.3) | 29 (16.9) | |
| Weekly | 102 (19.9) | 39 (22.7) | |
| Daily | 59 (11.5) | 28 (16.3) | |
| Chest pain | |||
| Never | 153 (30.4) | 44 (25.3) | 0.46 |
| Infrequently/quarterly | 104 (20.6) | 41 (23.6) | |
| Monthly | 93 (18.5) | 33 (19.0) | |
| Weekly | 106 (21.0) | 33 (19.0) | |
| Daily | 48 (9.5) | 23 (13.2) | |
| Upper abdominal pain | |||
| Never | 98 (19.3) | 18 (10.3) | <0.0001 |
| Infrequently/quarterly | 81 (15.9) | 22 (12.6) | |
| Monthly | 98 (19.3) | 28 (16.0) | |
| Weekly | 142 (27.9) | 39 (22.3) | |
| Daily | 90 (17.7) | 68 (38.9) | |
| Lower abdominal pain | |||
| Never | 152 (29.9) | 16 (9.3) | <0.0001 |
| Infrequently/quarterly | 88 (17.3) | 16 (9.3) | |
| Monthly | 97 (19.1) | 34 (19.7) | |
| Weekly | 104 (20.5) | 51 (29.5) | |
| Daily | 67 (13.2) | 56 (32.4) | |
| Bloating | |||
| Never | 172 (34.0) | 23 (13.1) | <0.0001 |
| Infrequently/quarterly | 98 (19.4) | 26 (14.8) | |
| Monthly | 76 (15.0) | 29 (16.5) | |
| Weekly | 96 (19.0) | 45 (25.6) | |
| Daily | 64 (12.7) | 53 (30.1) | |
| Constipation | |||
| Never | 176 (34.9) | 42 (24.1) | 0.01 |
| Infrequently/quarterly | 103 (20.4) | 32 (18.4) | |
| Monthly | 79 (15.6) | 28 (16.1) | |
| Weekly | 86 (17.0) | 34 (19.5) | |
| Daily | 61 (12.1) | 38 (21.8) | |
| Diarrhea or loose stool | |||
| Never | 160 (31.5) | 22 (12.6) | <0.0001 |
| Infrequently/quarterly | 104 (20.5) | 28 (16.1) | |
| Monthly | 93 (18.3) | 33 (19.0) | |
| Weekly | 107 (21.1) | 44 (25.3) | |
| Daily | 44 (8.7) | 47 (27.0) | |
| Blood in stools | |||
| No | 393 (75.7) | 87 (49.2) | <0.0001 |
| Yes | 99 (19.1) | 74 (41.8) | |
| Do not know | 27 (5.2) | 16 (9.0) | |
| Vitamin deficiencies | |||
| No/unknown | 394 (72.0) | 94 (50.3) | <0.0001 |
| Yes | 153 (28.0) | 93 (49.7) | |
| Weight loss | |||
| No | 256 (49.3) | 58 (32.8) | 0.001 |
| Yes | 248 (47.8) | 113 (63.8) | |
| Do not know | 15 (2.9) | 6 (3.4) | |
| Gastroparesis | |||
| No/unknown | 474 (86.7) | 136 (72.7) | <0.0001 |
| Yes | 73 (13.4) | 51 (27.3) | |
EC= eosinophilic colitis; EG = eosinophilic gastritis; EGE = eosinophilic gastroenteritis; EGIDs = eosinophilic gastrointestinal diseases; EoE = eosinophilic esophagitis.
*
With or without concomitant EoE.