Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 15;10(7):200118. doi: 10.1098/rsob.200118

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

PMC Copyright notice

Figure 1. — Elements of Ca²⁺ toolbox in endoplasmic reticulum, mitochondria, lysosomes and plasma membrane of somatic cells. Orange dots indicate Ca²⁺; grey arrows show direction of Ca²⁺ flow. cADPR, cyclic ADP ribose; CAX, Ca²⁺/proton exchanger; IP3, inositol trisphosphate; IP3R, IP3 receptor; MCU, mitochondrial uniporter; NCLX, mitochondrial sodium–Ca²⁺ exchanger; NAADP, nicotinic acid adenine dinucleotide phosphate; NCX, sodium/Ca²⁺ exchanger; ORAI, Ca²⁺ release-activated Ca²⁺ channel protein; PIP2, phosphatidylinositol 4,5-bisphosphate; PLC, phospholipase C; PMCA, plasma membrane Ca²⁺ ATPase; RyR, ryanodine receptor; SERCA, sarco/endoplasmic reticulum Ca²⁺ ATPase pump; STIM, stromal interaction molecule; TPC, two-pore channel.