Fig. 2.

Histopathology slides from the vitrectomy and capsulotomy specimen. a Haematoxylin and eosin (H&E) stained cell block cytology preparation showing pieces of lens capsule (arrows) in amongst pigmented and non-pigmented cells. b Higher power H&E of plate a showing some cytologically atypical cells. Note the binucleate atypical cell towards the top left of the plate. c Melan A immunohistochemistry showing that some of the pigmented and non-pigmented cells are Melan A positive (red = positive). d Sox10 immunohistochemistry showing nuclear positivity of some of the cells (small arrows). The larger arrow points to a structure that is suspicious for a granuloma. e CD68 immunohistochemistry showing central confluent staining of several cells in a cluster, confirming the presence of granulomatous inflammation.