Table 2.

Remote monitoring in heart failure (HF) patients using implantable cardioverter defibrillator/cardiac resynchronisation therapy (ICD/CRT) devices

Trial/study	Author; journal; year	No. of patients	Parameter	Endpoint	Impact on HF hospitalisation
DOT-HF [16]	Van Veldhuisen et al.; Circulation; 2011	335	Intrathoracic impedance	HF hospitalisation	Increased
OptiLink [14]	Brachmann et al.; Eur J Heart Fail; 2011	1002	Intrathoracic impedance	HF hospitalisation	Non-significant
EFFECT [17]	De Simone et al.; Europace; 2015	987	Remote monitoring via ICD, or CRT	HF hospitalisation	Reduced (IRR 0.54; 95% CI 0.24–0.62)
MORE-CARE [13]	Boriani et al.; Eur J Heart Fail; 2017	865	Remote monitoring of advanced diagnostics via CRT‑D	HF hospitalisation	Non-significant
REM-HF [15]	Morgan et al.; Eur Heart J; 2017	1650	Remote monitoring via ICD, or CRT	HF hospitalisation	Non-significant
COMMIT-HF [18]	Kurek et al.; J Cardiovasc Electrophysiol; 2017	574	Remote monitoring via ICD, or CRT	HF hospitalisation/ All-cause mortality	Non-significant/ Reduced all-cause mortality (HR 0.24; 95% CI 0.14–0.41)
IN-TIME [19]	Hindricks et al; Lancet; 2014	716	Remote monitoring via ICD, or CRT	HF worsening score	OR 0.63 95% Ci 0.43–0.90