Figure 4.

CM-expressing rod photoreceptors have normal flash responses. A, Suction electrode recordings of families of responses to flashes that ranged from 6 to 52,500 photons/µm² with sequentially increased strength by factors of 2–4. Flashes were delivered at t = 0 s. B, Population average single-photon responses calculated from WT (n = 18) and CM77^arr−/− (n = 17) rods. Light shading represents SEM. C, Relationship between the time that a bright flash response remained in saturation and the natural log of the number of photoexcited rhodopsins (R*) produced by the flash. The initial slope reflects the dominant time constant of recovery for bright flashes, which was the same for mutant and WT rods. Error bars represent the SEM.