. 2020 Oct 14;40(42):8149–8159. doi: 10.1523/JNEUROSCI.2883-19.2020

Table 3.

Quality variables for the ¹H-MRS measurements^a

Region, age group	SNR	FWHM (Hz)	CRLB
Region, age group	SNR	FWHM (Hz)	mIns	tCr	tCho	tNAA	Glu
ACC
Younger	44.6 ± 10.5^**	7.87 ± 1.12^*	2.68 ± 0.57^*	1.21 ± 0.41^**	3.11 ± 0.45^*	1.05 ± 0.22^**	2.11 ± 0.32^**
Middle	36.4 ± 10.9^*	8.61 ± 0.91	3.40 ± 1.82	1.80 ± 0.77^*	3.60 ± 1.23	1.40 ± 0.75^**	2.80 ± 1.06^*
Older	30.3 ± 7.43^*	8.88 ± 0.98^*	3.52 ± 0.77^*	1.84 ± 0.50^*	3.89 ± 0.88^*	1.84 ± 0.37^**	3.16 ± 0.50^*
DLPFC
Younger	43.8 ± 13.8^*	11.7 ± 2.36^*	3.95 ± 1.88	1.63 ± 0.74	4.63 ± 1.35	1.32 ± 0.65	3.47 ± 1.35
Middle	35.3 ± 9.82	14.0 ± 3.40^*	3.35 ± 1.14	1.85 ± 0.49	4.40 ± 1.64	1.50 ± 0.51	3.65 ± 0.93
Older	31.6 ± 9.89^*	13.4 ± 1.77	4.00 ± 1.41	1.94 ± 0.52	4.29 ± 1.09	1.59 ± 0.48	4.06 ± 0.97
Hippocampus
Younger	27.4 ± 8.38^**	12.1 ± 1.76^**	3.58 ± 0.75^*	2.26 ± 0.44^*	4.47 ± 1.04	1.53 ± 0.50^**	3.68 ± 0.57^*
Middle	22.4 ± 5.14^*	14.5 ± 2.28^*	3.79 ± 1.69	2.58 ± 0.61	4.60 ± 1.53	1.90 ± 0.45^**	4.20 ± 0.77^*
Older	17.7 ± 4.36^*	15.8 ± 3.07^*	4.50 ± 1.12^*	2.83 ± 0.60^*	5.00 ± 1.80	2.22 ± 0.42^**	5.50 ± 1.17^**
Thalamus
Younger	22.4 ± 3.32^*	11.4 ± 1.47^*	5.68 ± 1.81	2.53 ± 0.50^*	4.63 ± 0.93	1.53 ± 0.50	5.42 ± 1.18^*
Middle	20.6 ± 3.90	12.1 ± 1.53	4.86 ± 1.43	2.75 ± 0.55	4.59 ± 1.23	1.69 ± 0.47	5.70 ± 1.03^*
Older	19.2 ± 4.78^*	13.2 ± 1.70^*	5.17 ± 1.54	3.06 ± 0.40^*	4.83 ± 1.50	1.83 ± 0.50	7.06 ± 2.61^**

^aData are mean ± SD. SNR, Signal-to-noise ratio.

Age groups that are pairwise significantly different (p < 0.05):

*different from one other group;

**different from both other groups.