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. 2020 Aug 31;4(10):e10398. doi: 10.1002/jbm4.10398

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© 2020 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig 1 — (A,C) forearm radiographs demonstrating bending wedge diaphyseal ulna fracture at injury and immediately postoperatively. (B,D) fForearm radiographs demonstrating simple fracture patterns of diaphyseal radius and ulna at injury and immediately post‐operatively. (E) Schematic of the human SSC lineage tree with a self‐renewing stem cell at the top of the hierarchy giving rise to a human bone/cartilage/stromal cell progenitor (hBCSP) and to lineage committed cartilage and bone/stromal cells (PDPN: Podoplanin). (F) Experimental workflow for SSC isolation from patient tissue. (G,H) FACS plots demonstrating isolation of SSCs from fractures immediately after surgery. (I) Frequency of hSSCS at fracture sites as percentage of non‐hematopoietic cells for normalization.