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. 2020 Oct 20;89:107088. doi: 10.1016/j.intimp.2020.107088

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Published by Elsevier B.V.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 5 — Cytokine levels of IL-1β, IL-6, TNF-α, and IL-18 in the Nano curcumin‐treated COVID-19 patients and placebo group in serum. Analysis showed a reduction in the secretion level of inflammatory cytokines, including IL-1β, IL-6 and TNF-α (P = 0.0082, 0.0038 and 0.037, respectively). (Nano-curcumin group number = 20, placebo group number = 20). Evaluation of cytokine secretion level was done by ELISA. Paired T test was used for statistical analysis and P < 0.05 was considered statistically significant.