TABLE 1.
Clinical and biochemical characteristics of the subjects, and the correlation coefficients between serum relaxin‐3 levels with different parameters in the study groups
| Variables | Controls (n = 45) | Renal calculus (n = 45) |
Relaxin‐3 Correlation coefficient (r) |
|---|---|---|---|
| Age (y) | 57 (25‐79) | 55 (25‐76) | .000 |
| Gender (male/female, n) | 22/23 | 22/23 | .070 |
| BMI (kg/m2) | 23.81 ± 3.43 | 24.01 ± 3.97 | .002 |
| Relaxin‐3 (pg/mL) | 30.53 ± 12.46 | 40.78 ± 30.95* | — |
| Scr (μmol/L) | 63.58 ± 12.38 | 97.59 ± 69.92** | .293** |
| BUN (mmol/L) | 5.77 ± 1.20 | 6.87 ± 3.32* | .278** |
| Cys‐c (mg/L) | 0.87 ± 0.14 | 1.17 ± 0.39** | .253* |
| β2‐MG (mg/L) | 1.39 ± 0.38 | 2.40 ± 1.59* | .338** |
| RBP (mg/L) | 43.06 ± 13.56 | 48.70 ± 14.42** | .239* |
Data expressed as means ± SEM, *P < .05 vs controls, **P < .01 vs controls. r = correlation coefficient, *P < .05, **P < .01.
Abbreviations: β2‐MG, β2‐microglobulin; Cys‐c, cystatin c; BMI, body mass index; BUN, blood urea nitrogen; RBP, retinol‐binding protein; Scr, serum creatinine.