Fig. 1.

Study schematic. Dosing with nebulised GSK2862277 26 mg or placebo. BAL, bronchoalveolar lavage; OLV, one-lung ventilation; OP, operation. ¹On completion of surgery, transpulmonary thermodilution measurement first then bronchoalveolar lavage were performed before tracheal extubation. ²Thermodilution performed if patient remained in ICU with patent indwelling PiCCO catheter.