Table 3. Associations of severe disease with listed conditions over all age groups.
| Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
| Controls (36,948) | Cases (4,272) | Rate ratio (95% CI) | p -Value | Rate ratio (95% CI) | p -Value | |
| Care home | 2,935 (8%) | 1,894 (44%) | 21.4 (19.1–23.9) | 8 × 10−644 | 14.7 (13.1–16.6) | 1 × 10−431 |
| Any prescription | 33,483 (91%) | 4,129 (97%) | 3.10 (2.59–3.71) | 8 × 10−35 | 1.83 (1.51–2.22) | 6 × 10−10 |
| Any admission | 22,538 (61%) | 3,457 (81%) | 2.75 (2.53–2.99) | 2 × 10−124 | 1.56 (1.41–1.72) | 1 × 10−18 |
| Type 1 diabetes | 158 (0%) | 43 (1%) | 2.75 (1.96–3.88) | 6 × 10−9 | 1.56 (1.05–2.32) | 0.03 |
| Type 2 diabetes | 5,542 (15%) | 909 (21%) | 1.60 (1.48–1.74) | 8 × 10−30 | 1.42 (1.29–1.56) | 3 × 10−13 |
| Other/unknown type | 283 (1%) | 48 (1%) | 1.74 (1.28–2.38) | 4 × 10−4 | 1.58 (1.11–2.27) | 0.01 |
| Ischaemic heart disease | 5,475 (15%) | 906 (21%) | 1.49 (1.37–1.61) | 3 × 10−21 | 1.08 (0.98–1.20) | 0.1 |
| Other heart disease | 8,610 (23%) | 1,749 (41%) | 2.23 (2.08–2.39) | 4 × 10−109 | 1.33 (1.22–1.46) | 2 × 10−10 |
| Asthma or chronic airway disease | 7,608 (21%) | 1,434 (34%) | 1.96 (1.83–2.10) | 2 × 10−78 | 1.54 (1.42–1.68) | 7 × 10−25 |
| Chronic kidney disease or transplant recipient | 202 (1%) | 97 (2%) | 4.06 (3.15–5.23) | 3 × 10−27 | 2.88 (2.13–3.89) | 7 × 10−12 |
| Neurological (except epilepsy) or dementia | 3,282 (9%) | 1,381 (32%) | 5.4 (4.9–5.8) | 1 × 10−354 | 2.00 (1.81–2.21) | 2 × 10−42 |
| Liver disease | 133 (0%) | 51 (1%) | 3.61 (2.60–5.00) | 2 × 10−14 | 1.93 (1.32–2.81) | 6 × 10−4 |
| Immune deficiency or suppression | 143 (0%) | 40 (1%) | 2.66 (1.86–3.79) | 7 × 10−8 | 1.67 (1.10–2.52) | 0.01 |