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. 2020 Oct 8;16(10):e1008971. doi: 10.1371/journal.ppat.1008971

Fig 9. Effect of HSV-1 infection on T cell exhaustion in TG of latently infected mice.

Fig 9

TG from latently infected WT, M2-/-, and M2-OE mice were individually isolated on day 28 PI and qRT-PCR was performed using total RNA as described in the Materials and Methods. CD4, CD8, PD1, and Tim3 expression in naive mice for each group was used as a baseline to estimate relative expression of each transcript in TG of latently infected mice. GAPDH expression was used to normalize the relative expression of each transcript. Each point represents the mean ± SEM from 10 TG per group. Panels: A) CD4 transcript; B) CD8 transcript; C) PD1 transcript; and D) Tim3 transcript.