TABLE 3.

Relevant biologic processes in mitochondria modules

Module	Term ID	Term name	Total genes	Genes	Enrichment P
Mitochondrial function I: Energy generation and regulation of oxidative stress	GO:0019752	Carboxylic acid metabolic process	458	158	3.82 × 10−13
	GO:0006082	Organic acid metabolic process	530	170	5.85 × 10−11
	GO:0044281	Small molecule metabolic process	1213	324	1.09 × 10−10
	GO:0055114	Oxidation-reduction process	517	165	2.59 × 10−10
	GO:0046395	Carboxylic acid catabolic process	109	54	1.85 × 10−09
	GO:0051186	Cofactor metabolic process	175	73	6.85 × 10−09
	GO:0006520	Cellular amino acid metabolic process	192	72	3.91 × 10−06
	GO:0032787	Monocarboxylic acid metabolic process	272	92	8.29 × 10−06
	GO:0009063	Cellular amino acid catabolic process	60	32	1.77 × 10−05
	GO:0006631	Fatty acid metabolic process	162	62	2.74 × 10−05
	GO:0006637	Acyl-CoA metabolic process	40	24	9.37 × 10−05
Mitochondrial function II: Regulation of mitochondrial translation	GO:0006415	Translational termination	77	55	2.23 × 10−43
	GO:0006414	Translational elongation	90	58	6.71 × 10−42
	GO:0006413	Translational initiation	125	64	7.32 × 10−38
	GO:0019083	Viral transcription	85	47	6.96 × 10−29
	GO:0006613	Cotranslational protein targeting to membrane	45	35	1.43 × 10−28
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	45	35	1.43 × 10−28
	GO:0045047	Protein targeting to ER	48	36	1.77 × 10−28
	GO:0000184	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	58	39	4.03 × 10−28
	GO:0072599	Establishment of protein localization to endoplasmic reticulum	50	36	2.09 × 10−27
	GO:0043624	Cellular protein complex disassembly	131	56	2.32 × 10−27
	GO:0043043	Peptide biosynthetic process	271	80	3.95 × 10−27
	GO:0000956	Nuclear-transcribed mRNA catabolic process	87	46	5.00 × 10−27
	GO:0006412	Translation	259	78	5.23 × 10−27

Significant gene GO Biologic Processes within the mitochondria function modules.

GO, gene ontology.