Table 2.
Timing of moderate and mild infusion-related adverse events.
| Infusion-related adverse effect | Timing |
Intervention N reactions |
Withdrawal N patients |
||
|---|---|---|---|---|---|
| During |
After |
Unknown |
|||
| N patients I N reactions | |||||
| Moderate | |||||
| Delayed hypersensitivity | NA | 9 I 12 | NA | 3 | 1 |
| Hypotension | 2 I 2a | 0 I 0 | 0 I 0 | 1 | 0 |
| Nausea | 1 I 1 | 0 I 0 | 0 I 0 | 1 | 0 |
| Various | 4 I 6 | 2 I 2a | 0 I 0 | 5 | 0 |
| Vasovagal reactions | 8 I 8 | NA | NA | 9 | 0 |
| Mild | |||||
| Diarrhoea | 0 I 0 | 1 I 1 | 1 I 1 | 0 | 0 |
| Dizziness | 3 I 3a | 4 I 4 | 1 I 1 | 0 | 0 |
| Dyspnoea | 0 I 0 | 2 I 2 | 0 I 0 | 0 | 0 |
| Flushing | 1 I 1 | 0 I 0 | 0 I 0 | 1 | 0 |
| Headache | 1 I 1 | 4 I 4 | 5 I 5a | 2 | 0 |
| Nausea | 1 I 1a | 2 I 2 | 1 I 1 | 1 | 0 |
| Palpitations | 0 I 0 | 4 I 5a | 3 I 3 | 0 | 0 |
| Skin reactions | 1 I 1 | 2 I 2 | 2 I 2 | 0 | 0 |
| Thoracic pain | 1 I 1 | 0 I 0 | 0 I 0 | 0 | 0 |
| Vomiting | 0 I 0 | 1 I 1 | 1 I 1 | 0 | 0 |
a
These numbers include patients who experienced symptoms by every infusion.