Table 1.
Demographic and clinical measures.
| Intervention group (n = 15) | Control group (n = 14) | p value | |
|---|---|---|---|
| Age (years) | 38.1 (8.1) | 44.7 (7.5) | 0.028 |
| Gender (female/male) | 15/0 | 13/1 | 0.224 |
| Disease duration (years) | 9.9 (6.1) | 8.8 (5.8) | 0.641 |
| Body mass index | 23.7 (5.9) | 28.1 (3.3) | 0.026 |
| Handedness (right/left) | 13/2 | 13/1 | 0.584 |
| 6MWT pre (m) | 589.1 (56.2) | 577.2 (56.3) | 0.575 |
| 6MWT post (m) | 594.3 (49.7) | 578.6 (67.2) | 0.479 |
| SPART prea | 43.0 [41.0–48.0] | 44.5 [42.0–47.5] | 0.621 |
| SPART posta | 48.0 [44.0–53.0] | 43.5 [38.75–47.25] | 0.046 |
| SRT prea | 51.5 [43.75–54.0] | 51.5 [47.5–53.0] | –b |
| SRT posta | 50.0 [38.0–56.0] | 52.5 [42.75–59.25] | –b |
| NGMV (mL) | 810.3 (43.5) | 798.1 (21.4) | 0.344 |
| NHipV (mL) | 10.7 (7.5) | 10.8 (10.3) | 0.710 |
| Lesion volume (mL) | 6.0 [3.8–6.7] | 4.4 [3.7–6.2] | 0.505 |
6MWT = 6-minute walk test; SPART = spatial recall test; NGMV = normalized gray matter volume; NHipV = normalized bilateral hippocampus volume.
Values are mean (SD) unless otherwise specified. Values in bold significant at p<.05.
a
Median [IQR]; tested with Mann–Whitney U due to non-normal distribution.
b
No group comparisons performed due to absence of significant group*time interaction.