Table 5.
Comparison of clinical characteristics of apatinib and other novel antigens for relapsed and refractory NPC
Drug | Study | N | ORR | PFS | OS |
---|---|---|---|---|---|
Axitinib | Hui et al. | 37 | 19% | 5 months | 10.4 months |
Nivolumab | Ma et al. [20] | 32 | 13% |
3.5 months 3-month PFS, 64.2% |
3-month OS, 87.5% OS was not reached |
Pazopanib | Lim et al. [29] | 33 | 6.1% | 4.4 months | 1-year OS, 32% |
Interleukin-2 | Chi et al. [30] | 14 | 0 | – | 9 months |
Adoptive T cell therapy | Smith et al. [22] | 29 | – | 5.5 months | 38.1 months |