Table 3.

Comparison of the number of children and adolescents with neurofibromas (nf). The comparison included two groups of age-matched patients, those with NF1 microdeletions analysed in the present study and the NF1 patients of the cohort reported by Duong et al. [49]. The patients analysed by Duong et al. were not selected pertaining to NF1 mutation type and hence represent the general NF1 population. The patients analysed were ≥ 10–19 years of age

	Number of patients analysed by Duong et al. [49]	Number of patients with NF1 microdeletions analysed in this study	p valuea
Number of cutaneous nf
0–1	131 (77%)	2 (10%)	6.6 × 10−9
≥ 2	40 (23%)	18 (90%)
Number of subcutaneous nf
0–1	127 (74%)	7 (33%)	0.0002
≥ 2	44 (26%)	14 (67%)

^aTwo-tailed Fisher’s exact test