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. 2020 Oct 20;10:17726. doi: 10.1038/s41598-020-74839-7

Table 1.

Donor-, recipient- and allograft characteristics.

Recipient p-value
HOPE (N = 15) CCS (N = 30)
Age 60 ± 9 60 ± 10 0.809
BMI 26 ± 6 27 ± 6 0.386
Sex ratio (female:male) 7:8 (47%:53%) 11:19 (36%:64%) 0.519
CCia 4.7 ± 1.8 4.7 ± 1.6 0.980
EPTSb 60 ± 19 58 ± 20 0.736
Etiology of ESRD

ADPKD: 7 (47%)

Diabetic KD: 1 (7%)

Hypertensive KD: 0 (0%)

Nephritis: 5 (33%)

Other: 2 (13%)

ADPKD: 4 (13%)

Diabetic KD: 2 (7%)

Hypertensive KD: 4 (13%)

Nephritis: 11 (37%)

Other: 9 (30%)

0.103
Donor p-value
HOPE (N = 15) CCS (N = 30)
Age 66 ± 12 66 ± 8 0.847
BMI 28 ± 7 27 ± 4 0.981
Sex ratio (female:male) 9:6 (60%:40%) 16:14 (53%:47%) 0.671
Cause of death

CVA: 9 (60%)

Anoxia: 5 (33%)

Trauma: 1 (7%)

CVA: 19 (64%)

Anoxia: 10 (33%)

Trauma: 1 (3%)

0.941
Diabetes mellitus

Yes: 8 (53%)

No: 6 (40%)

Unknown: 1 (7%)

Yes: 10 (33%)

No: 12 (40%)

Unknown: 8 (27%)

0.233
Arterial hypertension

Yes: 8 (53%)

No: 5 (33%)

Unknown: 2 (14%)

Yes: 17 (57%)

No: 5 (16%)

Unknown: 8 (27%)

0.355
Diuresis last 24 h (ml) 2 550 ± 1 800 3 180 ± 2 300 0.224
KDPI 87 ± 14 87 ± 18 0.708
Serum crea (mg/dl) 1.9 ± 1.4 1.4 ± 0.7 0.457
CIT (min) 646 ± 227 674 ± 214 0.563
WIT (min) 36 ± 9 36 ± 11 0.843

Values are given as mean ± standard deviation or numbers and (percent).

HOPE, hypothermic oxygenated machine perfusion; CCS, conventional cold storage; BMI, body mass index; CCi, charlson comorbidity index; KDPI, Kidney donor profil index; EPTS, estimated post-transplant survival; ESRD, end-stage renal disease; CIT, cold ischemia time; WIT, warm ischemia time.

aAccording to Charlson et. al.33.

bAccording to Organ Procurement and Transplantation Network45.