Table 2.
4’OH E7.75 | 4’OH E8.75 | 4’OH E9.5 | 4’OH E10.5 | |||||
---|---|---|---|---|---|---|---|---|
Ctrl | Nkx2-5+/− | Ctrl | Nkx2-5+/− | Ctrl | Nkx2-5+/− | Ctrl | Nkx2-5+/− | |
Total hearts | 4 | 4 | 13 | 5 | 20 | 14 | 5 | 8 |
Total clones | 19 | 19 | 82 | 28 | 179 | 64 | 37 | 48 |
Frequency/LV | 4.75 | 4.75 | 6.3 | 5.6 | 9.0 | 4.6 | 7.4 | 6.0 |
% cond. clones* | 37 | 26 | 58.5 | 46.4 | 73.7 | 60.9 | 81.1 | 66.7 |
% mixed clones* | 63 | 74 | 41.5 | 53.6 | 26.3 | 39.1 | 18.9 | 33.3 |
Size cond. clones | 15.7 | 10.5 | 9.4 | 5.4 | 10.2 | 10.4 | 7.0 | 5.8 |
Size mixed clones | 156.25 | 96.1 | 68.6 | 32.7 | 47.5 | 39.8 | 72.4 | 31.9 |
Size cond. in mixed | 20.4 | 13.1 | 24.1 | 7.5 | 14.1 | 10.7 | 7.3 | 4.5 |
Table represents the n values of hearts and clones analyzed in this study, using Sma-CreERT2::R26R-Confetti mouse line. Asterisks shows percentages of conductive clones versus mixed clones. Non-conductive clones are excluded from the analysis.