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. 2020 Oct 20;11:5067. doi: 10.1038/s41467-020-18784-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Skin sections from two healthy controls (left panels) and from three acne vulgaris patients presenting with lesions of increasing severity (right panels) stained with haematoxylin and eosin (H&E), or labelled with antibodies against GATA6, Ki67, and KRT5/6 (brown labelling). Scale bar: 100 μm. b Expression of GATA6 transcripts (210002_at probe) was assessed in unaffected skin and acne lesions from microarray datasets GSE53795 (n = 12 control skin, n = 12 acne skin; p = 0.00006) and GSE6475 (n = 12 control skin, n = 6 acne skin; p = 0.112). Mean and individual values are presented. ns not significant; ***p-value < 0.0005; two-tailed unpaired t-test. Source data are provided as a Source Data file.