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. 2020 Oct 20;11(10):879. doi: 10.1038/s41419-020-03101-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A IPO13 protein levels were examined by western blot in normal epithelial lung cell HBE, and NSCLC cell lines (A549, H1299, and H1975); quantitation of relative IPO13 protein expression compared to HBE. The data were represented as mean ± S.D., Student’s t test (n = 3, *P < 0.05, **P < 0.01). B Analysis of IPO13 expression in lung cancer from Oncomine database. C Boxplots comparing IPO13 expression levels in the normal lung (65), large-cell lung carcinoma (19), lung adenocarcinoma (45), and squamous cell lung carcinoma (27) in 156 samples from Oncomine database. D The expression of IPO13 in lung cancer tissues and adjacent normal lung tissues from eight cases was detected by western blotting. E Immunohistochemical analysis of IPO13 expression in NSCLC tumor tissue and adjacent normal tissues (scale bar = 100 μm). F Based on IHC analysis, the number of cases with high and low levels of IPO13 are shown.