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. 2020 Oct 20;10:17787. doi: 10.1038/s41598-020-74246-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Alterations of metabolites and possible metabolic pathways in myocardial tissues and serum. The metabolites in blue font were altered in MI and metabolic pathways in red font were regulated by the new crystal form of puerarin. And the different colors of arrows represent the altered trends of metabolites that were regulated by the new crystal form of puerarin in the serum and myocardial tissues (red represented the serum, and green represented the myocardial tissues) in the Pue-L or Pue-H groups compared with the model groups, respectively.