Table 2.
Monthly sampling and detection rates of germline BRCA1/2 PVs over three eras in the North West of England.
| Era | No. tested | gBRCA1/2 PV | Monthly sampling rate | Monthly detection rate |
|---|---|---|---|---|
| January 2007 to May 2013 (20% threshold) Period 1 | 183 | 61 (33.3) | 2.38 | 0.79 |
| June 2013 to October 2017 (10% threshold) Period 2 | 418 | 72 (17.2) | 7.89 | 1.36 |
| November 2017 to November 2019 (mainstreaming) Period 3 | 480 | 89 (18.5) | 20 | 3.71 |
| Total | 1081 | 222 (20.5) | – | – |
Data presented as number or number (percentage).
gBRCA1/2 PVs germline BRCA1/2 pathogenic variants.