Table 3.
Germline BRCA1/2 PVs detected in non-mucinous EOC index cases from January 2007 to November 2019 in the North West of England categorised according to Manchester Score.
| Manchester Score (pathology adjusted) | No. tested | gBRCA1/2 PVs |
|---|---|---|
| Single ovary only, non-mucinous, ≥60 years old | 168 | 10 (6.0) |
| Single ovary only, non-mucinous, <60 years old | 294 | 35 (11.9) |
| Manchester Score <11 | 186 | 10 (5.4) |
| Manchester Score 11–14 | 126 | 11 (8.7) |
| Manchester Score 15–19 | 451 | 64 (14.2) |
| Manchester Score 20–24 | 131 | 44 (33.6) |
| Manchester Score 25–39 | 160 | 71 (44.4) |
| Manchester Score ≥40 | 27 | 22 (81.5) |
| Total | 1081 | 222 (20.5) |
Data presented as number or number (percentage).
gBRCA1/2 PVs germline BRCA1/2 pathogenic variants.