Figure 5.
Modified disk diffusion assay result with Candida albicans for an uncoated polyglycolic microneedle array (A), a matrix-assisted pulsed laser evaporation-coated microneedle array from deposition with the AmfB(260) target (amphotericin B 1040 mg/mL + 1% polyvinylpyrrolidone (noted as AB (260)), and a matrix-assisted pulsed laser evaporation-coated microneedle array from deposition with the AmfB(520) target (amphotericin B 2080 mg/mL + 1% polyvinylpyrrolidone) (noted as AB (520)) (B). Zones of growth inhibition were noted surrounding the matrix-assisted pulsed laser evaporation-coated microneedle arrays. In addition, zones of inhibition were noted surrounding pieces of glass (C) and silicon (D) wafer that were coated with the AmfB(260) target and the AmfB(520) target using matrix-assisted pulsed laser evaporation.