Table 1.

Genetic correlations of platelet parameters with (A) Parkinson’s disease and (B) Alzheimer’s disease risk, based on LD score regression analyses.

A
Platelet parameter	#SNPsa	rg	SE	Z-score	p
Plt	916,946	-0.033	0.031	-1.07	0.28
MPV	916,936	0.046	0.031	1.47	0.14
PDW	916,712	0.080	0.034	2.35	0.019
B
Platelet parameter	#SNPsa	rg	SE	Z-score	p
Plt	1,123,504	0.016	0.052	0.30	0.77
MPV	1,123,487	0.010	0.051	0.19	0.85
PDW	1,123,214	-0.088	0.053	-1.66	0.096

Significant genetic correlations (p < 0.05) are highlighted in bold.

^aExact numbers of SNPs used to compute each pairwise genetic correlation (i.e., in common between the studies analyzed).

Plt, platelet count; MPV, mean platelet volume; PDW, platelet distribution width; SNPs, Single Nucleotide Polymorphisms; rg (SE), genetic correlation and relevant Standard Error.