Skip to main content
Springer Nature - PMC COVID-19 Collection logoLink to Springer Nature - PMC COVID-19 Collection
. 2020 Oct 21;25(9):1197–1213. doi: 10.1007/s12045-020-1039-2

Hydra: A Powerful Biological Model

Surendra Ghaskadbi 1,
PMCID: PMC7575702

Abstract

Hydra, a freshwater diploblast, with a simple but defined body plan, an organized nervous system, and the presence of stem cells, is one of the oldest model organisms used in biology. It exhibits many embryonic features even as an adult, a spectacular ability of regeneration, and lack of organismal aging. Hydra can provide insights into how complex animal forms evolved and is waiting to be better utilized in teaching.

Keywords: Hydra, regeneration, pattern formation, model system, teaching tool

Acknowledgements

I am grateful to Vidya Patwardhan and Satyajit Rath for critical reading of the draft manuscript and suggesting changes. I thank Dr Sujata Deshpande, Ms Rohini Londhe, and Mr Ma-hadeo Daware for various inputs. Over the past two decades, my hydra laboratory has been funded by the Departments of Science & Technology (DST) and Biotechnology (DBT), Science and Engineering Research Board (SERB), Government of India, and MACS-Agharkar Research Institute. Surendra Ghaskadbi is an Emeritus Scientist of Council for Scientific and Industrial Research, New Delhi

Footnotes

Surendra Ghaskadbi is a developmental biologist particularly interested in cell signaling during pattern formation and evolution of developmental mechanisms. Over the past two decades he has reintroduced hydra as a model system for teaching and research in India.

Suggested Reading

  • [1].Ratcliff M J. The Trembley effect or the birth of marine zoology. Int, J, Dev. Biol. 2012;56:425–436. doi: 10.1387/ijdb.123520mr. [DOI] [PubMed] [Google Scholar]
  • [2].Technau U, Steele R E. Evolutionary crossroads in developmental biology. Development. 2011;138:1447–1458. doi: 10.1242/dev.048959. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • [3].Martinez D E, Bridge D. Hydra, the everlasting embryo confronts aging. Int. J. Dev. Biol. 2011;56:479–487. doi: 10.1387/ijdb.113461dm. [DOI] [PubMed] [Google Scholar]
  • [4].Browne E N. The production of new hydranths in hydra by the insertion of small grafts. J. Exp. Zool. 1909;7:1–23. doi: 10.1002/jez.1400070102. [DOI] [Google Scholar]
  • [5].Kadu V, Ghaskadbi S S, Ghaskadbi S. Induction of secondary axis in hydra revisited. Int. J. Mol. Cell. Med. 2012;1:11–20. [PMC free article] [PubMed] [Google Scholar]
  • [6].N Vargesson, Positional information — A concept underpinning our understanding of developmental biology, Dev. Dyn., DOI 10.1002/dvdy.116. [DOI] [PubMed]
  • [7].Ghaskadbi S. Cell signaling molecules in hydra: insights into evolutionarily ancient functions ofsignaling pathways. Int. J. Dev. Biol. 2020;64:141–149. doi: 10.1387/ijdb.190243sg. [DOI] [PubMed] [Google Scholar]
  • [8].Londhe R, Krishnapati L S, Ghaskadbi S. Description and phylogenetic characterization of hydra from Naukuchiatal (Uttarakhand, India) and comparison with other hydra strains. Curr. Sci. 2017;113:1739–1745. doi: 10.18520/cs/v113/i09/1739-1745. [DOI] [Google Scholar]
  • [9].Patwardhan V, Ghaskadbi S. Invertebrate alternatives for toxicity testing: Hydra stakes its claim. ALTEX Proc. 2013;2:69–76. [Google Scholar]
  • [10].Sugiyama T, Fujisava T. Genetic analysis of developmental mechanisms in hydra I. Sexual reproduction of Hydra magnipapillata and isolation of mutants. Dev. Growth Diff. 1977;19:187–200. doi: 10.1111/j.1440-169X.1977.00187.x. [DOI] [PubMed] [Google Scholar]
  • [11].Hoffmeister S, Chica Schaller H. A new biochemical marker for foot-specific cell differentiation in hydra. Roux’s Dev Biol. 1985;194:453–461. doi: 10.1007/BF00868146. [DOI] [Google Scholar]

Articles from Resonance are provided here courtesy of Nature Publishing Group

RESOURCES