Table 1. Characteristics of SARS-CoV-2-infected patients with fever.
| Characteristics | Total (n=77) | Non-ARDS (n=63) | ARDS (n=14) | P value |
|---|---|---|---|---|
| Age, years, mean (SD) | 47.99±15.75 | 46.37±15.65 | 55.29±14.57 | 0.055 |
| Gender, n (%) | 0.073 | |||
| Female | 33 (42.86%) | 30 (47.62%) | 3 (21.43%) | |
| Male | 44 (57.14%) | 33 (52.38%) | 11 (78.57%) | |
| Hubei exposure | 52 (67.53%) | 42 (66.67%) | 10 (71.43%) | 0.731 |
| Systolic pressure, mmHg, mean (SD) | 124.47±11.87 | 124.95±11.88 | 122.29±12.03 | 0.451 |
| Diastolic pressure, mmHg, mean (SD) | 78.30±8.96 | 78.70±9.17 | 76.50±8.03 | 0.410 |
| Heart rate, beats per min, mean (SD) | 91.01±13.87 | 88.73±13.44 | 101.29±11.16 | 0.002 |
| Respiratory rate, IQR | 20 [20, 21] | 20 [20, 20] | 21.5 [20, 23] | <0.001 |
| Days from illness onset to first hospital admission (days), IQR | 5 [3, 7] | 5 [3, 7.5] | 4.5 [3, 6.75] | 0.779 |
| Signs and symptoms, n (%) | ||||
| Fatigue | 32 (41.56%) | 27 (42.86%) | 5 (35.71%) | 0.624 |
| Cough | 48 (62.34%) | 38 (60.32%) | 10 (71.43%) | 0.438 |
| Anorexia | 2 (2.60%) | 2 (3.17%) | 0 (0.00%) | 0.499 |
| Myalgia | 8 (10.39%) | 6 (9.52%) | 2 (14.29%) | 0.597 |
| Dyspnea | 11 (14.29%) | 5 (7.94%) | 6 (42.86%) | <0.001 |
| Expectoration | 20 (25.97%) | 18 (28.57%) | 2 (14.29%) | 0.270 |
| Sore throat | 5 (6.49%) | 5 (7.94%) | 0 (0.00%) | 0.276 |
| Dizziness | 3 (3.90%) | 3 (4.76%) | 0 (0.00%) | 0.405 |
| Headache | 7 (9.09%) | 5 (7.94%) | 2 (14.29%) | 0.455 |
| Any comorbidity, n (%) | ||||
| Hypertension | 14 (18.18%) | 9 (14.29%) | 5 (35.71%) | 0.060 |
| Cardiovascular disease | 3 (3.90%) | 2 (3.17%) | 1 (7.14%) | 0.488 |
| Diabetes | 4 (5.19%) | 3 (4.76%) | 1 (7.14%) | 0.717 |
| Laboratory tests | ||||
| White blood cell count, ×109/L, mean (SD) | 4.52±1.52 | 4.62±1.41 | 4.07±1.91 | 0.076 |
| Neutrophil count, ×109/L, mean (SD) | 3.05±1.30 | 3.04±1.20 | 3.14±1.72 | 0.787 |
| Lymphocyte count, ×109/L, mean (SD) | 1.52±3.63 | 1.69±4.00 | 0.75±0.34 | 0.001 |
| Hemoglobin, g/L, mean (SD) | 130.16±21.49 | 128.98±22.67 | 135.43±14.62 | 0.313 |
| Platelet count, ×109/L, mean (SD) | 173.06±113.71 | 177.16±123.21 | 154.64±52.43 | 0.506 |
| C-reactive protein, mg/L, mean (SD) | 19.8 (8.6, 39) | 16.2 (7.6, 38.1) | 33 (21.9, 74.8) | 0.011 |
| Procalcitonin, ng/mL, IQR | 0.05 (0.05, 0.05) | 0.05 (0.05, 0.05) | 0.05 (0.05, 0.05) | 0.465 |
| Erythrocyte sedimentation rate, mm/h, IQR | 48 [27, 72] | 46 [25, 77] | 51.5 [45.5, 66] | 0.837 |
| Alanine aminotransferase, U/L, mean (SD) | 24.90±12.84 | 24.44±13.01 | 26.98±12.29 | 0.507 |
| Aspartate aminotransferase, U/L, mean (SD) | 30.09±14.03 | 27.87±11.63 | 40.08±19.32 | 0.003 |
| Albumin, g/L, IQR | 37 [34.7, 39.1] | 38 [35, 40] | 34 [31.9, 35.6] | 0.002 |
| Total bilirubin, mmol/L, mean (SD) | 12.64±5.21 | 12.61±5.29 | 12.79±5.07 | 0.909 |
| Direct bilirubin, mmol/L, mean (SD) | 4.64±2.39 | 4.52±2.30 | 5.19±2.78 | 0.343 |
| Lactate dehydrogenase, U/L, mean (SD) | 204.30±75.70 | 187.88±61.97 | 278.20±89.41 | <0.001 |
| Creatinine, μmol/L, mean (SD) | 56.17±24.66 | 56.78±26.57 | 53.42±13.36 | 0.648 |
| Blood urea nitrogen, mmol/L, mean (SD) | 4.43±1.87 | 4.26±1.89 | 5.18±1.60 | 0.097 |
| Uric acid, μmol/L, mean (SD) | 258.68±99.46 | 261.41±104.09 | 246.41±77.22 | 0.613 |
| Prothrombin time, s, mean (SD) | 11.95±0.98 | 11.83±1.00 | 12.50±0.67 | 0.020 |
| Activated partial thromboplastin time, s, mean (SD) | 32.94±3.57 | 33.06±3.66 | 32.39±3.20 | 0.526 |
| D-dimer, ug/mL, IQR | 0.2 (0.1-0.4) | 0.2(0.1, 0.4) | 0.4 (0.1, 0.5) | 0.065 |
| Chest radiography, n (%) | ||||
| Unilateral pneumonia | 6 (7.79%) | 6 (9.52%) | 0 (0.00%) | 0.229 |
| Bilateral pneumonia | 64 (83.12%) | 50 (79.37%) | 14 (100.00%) | 0.062 |
SARS-CoV-2, severe acute respiratory syndrome coronavirus-2; ARDS, acute respiratory distress syndrome; IQR, interquartile range; SD, standard deviation.